This game plays perfectly.
PC Specs:
OS: Windows 7 Home Edition - 64-bit
CPU: AMD Athlon II Dual-Core M300, 2.0 GHz
GPU: ATI Radeon Mobility HD 4200 256MB
Memory: 4GB DDR2
Dolphin Version:
Dolphin SVN RC1 and R4869 - 64-Bit
Emulator settings:
(Core Settings)
Enable Dual Core
Enable Idle Skipping
HLE the IPL
Jit Recompiler
DSP on Thread
(Video Settings)
DX9
Safe Texture Cache
Enable EFB Copy to Texture
This is the other game mode known as "Germ Buster" That actually uses the Wii-motes motion to manipulate the pieces.
Asus Laptop: K53TA
OS: Windows 7 Home Premium, 64-Bit - SP1
CPU: AMD Llano A6-3400M, Quad-Core, 1.4GHz-2.6GHz (Overclocked)
GPU: AMD Radeon HD6650M, 1GB GDDR3 (Catalyst 13.1)
RAM: Samsung 4GB DDR3-1333
OS: Windows 7 Home Premium, 64-Bit - SP1
CPU: AMD Llano A6-3400M, Quad-Core, 1.4GHz-2.6GHz (Overclocked)
GPU: AMD Radeon HD6650M, 1GB GDDR3 (Catalyst 13.1)
RAM: Samsung 4GB DDR3-1333