I got my EU copy today and tested it on Dolphin 3.0-496.
It runs very well, actually! Compared to the original title the framerate is better on my system, there is still only a little bit of slowdown but it's entirely tolerable.
When I ran it on JIT recompiler I did experience two crashes, but there's no such problem when using JITIL.
There is some graphical inaccuracy when you disable XFB, such as the background effects for the intro with Reshiram and Zekrom.
Correct Reshiram (XFB enabled)
Incorrect Reshiram (XFB disabled)
Disabling XFB has a much smoother framerate however, enabled XFB may still read a full 30FPS but it is visibly choppy. That may just be my graphics card.
There are audio issues whenever a video plays such as a pre-rendered cutscene that introduces the areas in Poképark 2 or another one. My third cutscene did not have an audio issue however. The audio seems to "toggle" between sort of drowned out and softer, to louder and crisper, about a second between toggles.
There may also be a minor visual issue depending on how the game tries to display the graphics, the visuals are much more ambitious than the original poképark and tries to push the graphics engine a bit further, meaning even with an increased internal resolution, there may still be some visual jaggies on character models, like in
this screenshot.
It's a 1280x720 screenshot using 2x Native resolution, look at Piplup's eye and it's visibly unsmooth. Increasing the native resolution as high as 4x even won't resolve it.
Enabling Anti-aliasing helps, but on my HD4850 this is pretty slow.
As before with the first poképark game, or any game that uses internal snapshots such as Brawl or Wind Waker, EFB copy to RAM is necessary for accurate screenshots. This feature is stable on JITIL and does not crash.
Overall however the game runs admirably well with no significant or breaking issues. The game itself seems to be a significant improvement over the original in story telling, character interaction, graphics, audio, and skill games.
I look forward to continuing to play this game through Dolphin, only if I encounter some sort of major issue or if framerate diminishes to an uncomfortable level, will I instead play this on my Wii itself.
Edit: It looks like maybe I will be playing this on my Wii after all.
After a while longer, the framerate dips lower as more pokémon visit, just as before. I've experienced a random crash when looking in the collections sub-menu, and just now a very random crash, the game quitting to the desktop after freezing, no error message, or a "This program is not responding" message box
There's progress to be made it seems.