If you really certain you ISO isn't corrupt (I would suggest Checking Partition Integrity with Dolphin, to be sure), your NAND might me messed. Check your NAND (Tools => Check NAND) then perform an online update (Tools => Perform Online System Update) then try again.
I also own this game and can confirm it's still working perfectly fine in current development version (5.0-6302 at the time of this post)...
I also own this game and can confirm it's still working perfectly fine in current development version (5.0-6302 at the time of this post)...
Avell A70 MOB: Core i7-11800H, GeForce RTX 3060, 16 GB DDR4-3200, Windows 11 (Insider Preview)
ASRock Z97M OC Formula: Pentium G3258, GeForce GT 440, 16 GB DDR3-1600, Windows 10 (22H2)
ASRock Z97M OC Formula: Pentium G3258, GeForce GT 440, 16 GB DDR3-1600, Windows 10 (22H2)