General Settings:
Tested on r7120M.
D3D Settings:
Safe Texture Cache must be on at least fast to get rid of glitches.
DSP Settings:
LLE (recompiler) on thread works perfectly with no sound issues I can hear. HLE also works.
Overall:
The game runs perfect at 100% speed (100% of the time on my system) with above settings, with no issues of any kind! The game is all 2d therefore upscaling doesn't increase the image quality. Running it in a low resolution is an option if you get poor performance.
Screenshots/Videos: