If you're going for upscaled at the best it can be, then on a 1080p screen going above 4x IR is kinda useless because your monitor can't display anything higher. Then start applying AA/AF until the games run slowly.
Do not open the Graphics settings while the game is running, since it will overwrite the per-game defaults that make the games run properly. Make a change, run the game and check how it plays, close the game, make a change, restart. (that's how I do it anyways)
Since you have Nvidia, using OpenGL is probably the best for speed and stability.
Do not open the Graphics settings while the game is running, since it will overwrite the per-game defaults that make the games run properly. Make a change, run the game and check how it plays, close the game, make a change, restart. (that's how I do it anyways)
Since you have Nvidia, using OpenGL is probably the best for speed and stability.

