Total Noob Here - How do I run Resident Evil 4 GC?

[JosJuice]

Most PC disc drives can't read GC/Wii discs at all. If you have one of the very few compatible drives, you need to use a specific program like Rawdump or Friidump to dump the disc. The only other option is to use a homebrew program running on a Wii to dump the disc. (It's also possible to do it on a GameCube, but that's much more complicated.) Either way, you can't run the game directly from the disc inserted in the disc drive, you need to dump it to a file first. Here are details on how to dump: https://wiki.dolphin-emu.org/index.php?title=Ripping_Games