For me what fixed the problem was turn on Dump Audio i was having the same problem in Resident evil 1 remake and as soon as a turn dump audio on the sound was clear
Processor: Athlon II X2 250 @ 3.6 GHz Motherboard: ASUS M3A78-CM Cooling: Thermalright Ultima-90 Memory: 6 Gigs Kingston Hyper-X DDR2 800MHZ 4-4-4-12 Video Card: Sapphire Vapor-X HD 4870 1GB PCI-E (800 Core 1000 Memory) Case: Antec Nine Hundred OS: Windows 7 Ultimate 64bit
