I don't recommend anyone to follow these steps unless they actually know what the steps do. (The third one is always fine to do, though, but it's not guaranteed to help.)
If moving the game to an SSD actually helps, please check whether you have Speed Up Disk Transfer Rate turned on. It needs to be turned off for better performance. Or is the problem related to disc I/O for Dolphin's config rather than the game? Is there really a point in applying your settings to all disks?
If moving the game to an SSD actually helps, please check whether you have Speed Up Disk Transfer Rate turned on. It needs to be turned off for better performance. Or is the problem related to disc I/O for Dolphin's config rather than the game? Is there really a point in applying your settings to all disks?