Yep, PCIe generations are backwards compatible, but will only run at the speed of the older part. You may not get the full performance you would if you were using a newer motherboard, but it won't be too far off, and will definitely be much better than what you've got now.
OS: Windows 10 64 bit Professional
CPU: AMD Ryzen 5900X
RAM: 16GB
GPU: Radeon Vega 56
CPU: AMD Ryzen 5900X
RAM: 16GB
GPU: Radeon Vega 56
