No response from controller

[Luciferus]

Hi guys, first time using Dolphin, and i'm playing Twilight Princess. I'm using an Xbox One controller, and it has been working wonderfully. However, just now, about 7 hours into the game, the rom isn't responding to any input. I tried switching back to a keyboard and no response there either. This is probably just an issue with the rom, but is there a workaround from a problem like this?