We're not magicians, start updating your profile with proper hardware information and if you're still on 4.0-9177, update your Dolphin build too, we don't offer support for anything older than the latest stable release (currently at 5.0). Then, post your audio settings. Which backend are you using? Are you using DSP HLE or LLE?
Avell A70 MOB: Core i7-11800H, GeForce RTX 3060, 16 GB DDR4-3200, Windows 11 (Insider Preview)
ASRock Z97M OC Formula: Pentium G3258, GeForce GT 440, 16 GB DDR3-1600, Windows 10 (22H2)
ASRock Z97M OC Formula: Pentium G3258, GeForce GT 440, 16 GB DDR3-1600, Windows 10 (22H2)
