Couple of things to try:
Config > Audio tab > Audio Backend > try using Cubeb
Graphics > General tab > Shader Compilation to Hybrid Ubershaders
Graphics > Enhancements tab > try turning down the Anti-Ailiasing and Anisotropic Filtering
Config > Audio tab > Audio Backend > try using Cubeb
Graphics > General tab > Shader Compilation to Hybrid Ubershaders
Graphics > Enhancements tab > try turning down the Anti-Ailiasing and Anisotropic Filtering

