How to save?

[Holysmoke]

I have a mario kart disc that I burned to an iso to play on dolphin.

when I start mario kart it says saving please dont touch power button or reset

then it says could not read from write to system memory

what do I do to get around this? thanks much

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I am trying to set the path under the gc tab. I am not sure why it wont save to that path