Apparently, someone has managed to run without the speed hack at full speed near the end of the game. I don't know if this is real or not.
https://forums.dolphin-emu.org/Thread-zelda-twilight-princess-4k-fullspeed-on-hyrule-without-zelda-tp-hyrule-hack
As you can see, the person has got all heart pieces, and the map has the shadows that show up normally on console or when you disable the speed hack. (The weird colours around the minimap seem to be due to Force Texture Filtering being enabled.)
https://forums.dolphin-emu.org/Thread-zelda-twilight-princess-4k-fullspeed-on-hyrule-without-zelda-tp-hyrule-hack
As you can see, the person has got all heart pieces, and the map has the shadows that show up normally on console or when you disable the speed hack. (The weird colours around the minimap seem to be due to Force Texture Filtering being enabled.)