You mentioned save states...Have you tried a native save. Sometimes save states can do crazy things that a native save load can eliminate. Not saying that is the issue, but it may be something to try.
i5-8600K @ 4.5 GHz
GeForce GTX 1080 SC2
ASRock Z370 Taichi LGA 1151
CORSAIR Vengeance LPX 16GB 2400 DDR4
SAMSUNG 970 EVO M.2 500GB PCIe SSD
Indigo Xtreme TIM
Phanteks Pro ES614P Black Steel Case
EVGA SuperNOVA 750W PSU
Windows 10 64-bit
GeForce GTX 1080 SC2
ASRock Z370 Taichi LGA 1151
CORSAIR Vengeance LPX 16GB 2400 DDR4
SAMSUNG 970 EVO M.2 500GB PCIe SSD
Indigo Xtreme TIM
Phanteks Pro ES614P Black Steel Case
EVGA SuperNOVA 750W PSU
Windows 10 64-bit