In the future, please try to make your own separate thread instead of posting in an old one. The last one you posted to was almost 5 years old, and we have rules against necroposting/bumping like that. I took the liberty to make a new thread for you, so use this for any issues you have about disconnected emulated Wiimotes.
What happens when you try pressing any buttons that you assigned to the emulated Wiimote? Does the game work then?
When you say that you "leave for 20 mins", are you leaving the game running or on some pause menu, then coming back to your computer? A simple workaround would be to 1) use Dolphin's built-in pause feature or 2) make a save state before you leave then restart Dolphin and reload the save state.
What happens when you try pressing any buttons that you assigned to the emulated Wiimote? Does the game work then?
When you say that you "leave for 20 mins", are you leaving the game running or on some pause menu, then coming back to your computer? A simple workaround would be to 1) use Dolphin's built-in pause feature or 2) make a save state before you leave then restart Dolphin and reload the save state.