Fast is safe enough for nearly every game, and safe is fast enough that it shouldn't cause any slowdowns, and is, in fact, enabled whenever custom textures are used. It really doesn't matter as a setting these days.
OS: Windows 10 64 bit Professional
CPU: AMD Ryzen 5900X
RAM: 48GB
GPU: Radeon 7800 XT
CPU: AMD Ryzen 5900X
RAM: 48GB
GPU: Radeon 7800 XT