Dell 7559 running poorly

[Sinistrality]

I've switched to DX12, and the resolution to native (640x528). My drivers are at 375.70, and I'm unsure of where to find Nvidia profiles, but I'm thinking that may be done already (first picture)? This improved FPS in Hunter to 40-50, Gauntlet remains at 25 fps. I've also downloaded XTU, but the multipliers are grayed out for me. I'm guessing this is my main issue then.