Don't know about 4.5Ghz but 1 guy in this forum (i forgot his nickname) burned his mobo after a long period of "stable overclocking" (Phenom II 965 @ 4.0GHz), he used aftermarket cooling . I'm not saying this will happen to you but be becareful !
You should start with 3.8Ghz
You should start with 3.8Ghz
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