Best setting for lower end PC?

[GarebearGaming]

My PC Specs:
Processor: Intel® Core™ i5-8250U CPU @ 1.60GHz 1.80GHz
Installed memory (RAM): 12.0 GB (11.9 GB usable)
System type: 64-bit Operating System, x64-based processor
Pen and Touch: Pen and Touch Support with 10 Touch Points
Graphics Card: Intel® UHD Graphics 620
Chip Type: Intel® UHD Graphics Family
DAC Type: Internal
Adapter String: Intel® UHD Graphics 620
Bios Info: Intel Video BIOS
Monitor 1: My HP Laptop/PC
Monitor 2: Philips 105S (105S2)
GB: 915
I'm On Core i5, The 8th Gen.