I have the same CPU/GPU combo you have. Here's what I tend to do:
-Leave the Nvidia Control Panel alone. Put it on high performance mode, and then set everything to their default (except for the power management, set it to maximum).
-Set fullscreen to auto, turn on the Vertex Streaming Hack, and set the IR to 3x, max AA/AF.
This works will everything I've played (LEGO Star Wars II, Mario Kart DD, One Piece G.A., Pokemon Colosseum/XD, Brawl, Melee, Sonic Colors, Tales of Symphonia, Wind Waker, Twilight Princess, to name a few).
Also, try out dev build 4.0-614. Its the one just before they took out the vertex Streaming Hack.
Also try these:
1) Update drivers, Windows updates, DirectX Web updater (some components may be missing), and latest version of Visual C++
2) Make sure under Power Management in Windows you're running in High Performance, and are plugged in to power
-Leave the Nvidia Control Panel alone. Put it on high performance mode, and then set everything to their default (except for the power management, set it to maximum).
-Set fullscreen to auto, turn on the Vertex Streaming Hack, and set the IR to 3x, max AA/AF.
This works will everything I've played (LEGO Star Wars II, Mario Kart DD, One Piece G.A., Pokemon Colosseum/XD, Brawl, Melee, Sonic Colors, Tales of Symphonia, Wind Waker, Twilight Princess, to name a few).
Also, try out dev build 4.0-614. Its the one just before they took out the vertex Streaming Hack.
Also try these:
1) Update drivers, Windows updates, DirectX Web updater (some components may be missing), and latest version of Visual C++
2) Make sure under Power Management in Windows you're running in High Performance, and are plugged in to power