The OP shouldn't get slowdowns that cause audio stuttering though; that never happened on the Wii. It sounds like Dolphin is indeed slowing down.
I know the OP has a GTX Titan, but they should really see if playing at 1x helps at all. We had issues where GPUs would run at low clocks when playing Dolphin some time ago. Dunno if those problems are still around, but it should be looked into.
I know the OP has a GTX Titan, but they should really see if playing at 1x helps at all. We had issues where GPUs would run at low clocks when playing Dolphin some time ago. Dunno if those problems are still around, but it should be looked into.